Hello Richard,
The best tip I could offer you is to use the Pause Game (or lower game speed to "0") early and often. There are so many things that occur in this game in the seeming "blink of an eye" while the game clock is running if one is not paying close attention to the details. and I, for one, don't like to miss anything. Almost ANYTHING you might want to do in the game is worth doing with the game clock paused. Plan your work, then work your plan...and then restart the game clock. I am probably quite anal when it comes to this matter, but this is how I get enjoyment from playing this great game. I used to just be concerned with what I was doing during a scenario or campaign, but I eventually broadened my horizon by watching everything and everybody. What joy!! It is as if a story is being played out right before your eyes, so why miss any of the pages and/or scenes. As an added bonus, I guarantee this game will make you laugh out loud when you least expected it would. And you will remember these moments the most, I am thinking. Long after you will have forgotten about a certain achievement or attained medal, these moments will stick with you. A most amazing and satisfying experience for anyone, indeed.....don't miss any of them.
I will relate two such personal experiences, hoping you will not mind my sharing of them. The first one occurred when I finally learned how to really make some money by using the Stock Market. Following many of the good people's advice in these threads, I was able to successfully manipulate my company's share price down to $1....yes ONE DOLLAR....I laughed so hard I nearly spilled my beverage. And I bought every share that was available (with the game paused of course) before anyone else had the chance. I owned every share of stock available and was 100% owner of my RR. I roared with glee yet again, when my next train pulled into it's next station, as the share price soared into the $300+ range. Timing can sometimes be everything in this game, and the pause mode sure aids us in that regard.
The second experience occurred when, as a result of attaining a majority of an AI opponent's shares, I attempted and succeeded in merging our two companies. In itself, this is not very noteworthy; happens all of the time. What happened after was what I remember the most. The Chairman of the dissolved Company decided to start another railroad, again quite typical. It was when he chose to name it Conrail that I nearly fell out of my seat. This is an amazing game.....and you will have some amazing moments ahead I am sure.
Main thing is...find a "style" of gameplay you enjoy, and do just that.....ENJOY!! Watch and be amazed!